They also lost quarterback Justin Feaster to a shoulder injury.
Feaster is dressing for practice this week, but he is questionable for Saturday's game with Louisiana College.
Even if he doesn't play, head coach Jimmie Keeling expects his team to show up and play hard.
If Feaster doesn't go, former Odessa Permian quarterback Taylor Byrd will be the Cowboys starter.
The Cowboys host Louisiana College at 2.